Location, location, location: The who, how and where of muscle mechanics
Event date:
Monday, Nov 29, 2021 - Monday, Nov 29, 2021 Export event
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This event will be held on November 29, 2021 from 5:00 pm - 7:00 pm CET.
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Localization proteomics has provided an unprecedented view on macromolecular machines and helps improve our understanding of basic cell biology and processes as diverse as sarcomere mechanics, compartmentalization within the sarcomplasma, and spliceosome function. With this short symposium, we will focus on connecting labs and institutions between continents in applying localization proteomics to heart and skeletal muscle mechanics as the field moves from cells to organoid, engineered tissue and animal models.
Submit abstract here: https://www.mdc-berlin.de/news/events/location-location-location-who-how-and-where-muscle-mechanics
This event is organized by BPS Members Dr. Michael Gotthardt, Max-Delbrück-Centrum für Molekulare Medizin, and Dr. Stephan Lehnart, Universitätsmedizin Göttingen.
Event Speakers
Senior Speakers: Manuel Mayr (King's College, London), Philipp Mertins (Max Delbrück Center, Berlin), and Jared Kushner (Columbia University, New York)
Event Schedule
Intro (5 min)
Session 1: Connecting Localization Proteomics and Cardiovascular Research (55 min)
Jared Kushner (Columbia University, New York): Localization Proteomics – State of the Art: The mechanism of the cardiac fight or flight response revealed and the promise of proximity proteomics (18+7)
Philipp Mertins (MDC, Berlin, Germany): Technology and Applications (10+5)
Manuel Mayr (King's College London, U.K.): Translational Proteomics in Heart Failure THE EXTRACELLULAR MATRIX IN HEART FAILURE: THE ROLE OF ADAMTS5 IN PROTEOGLYCAN REMODELLING (10+5)
Jared Kushner (Columbia University, New York):
Localization Proteomics – State of the Art (18 + 7 min.)
Philipp Mertins (MDC): Technology and Applications (10 + 5 min.)
Manuel Mayr (King's College, London): Translational Proteomics in Heart Failure (10 + 5 min.)
Session 2: Marketplace
Short talks / Elevator pitch (7 x 5+2 min.)
Wrap-up (+introduction breakout rooms - 5 min.)
Breakout rooms:
- Technology Q&A (Proteomics, Electrophysiology, Biomechanics)
- Matchmaking (Marketplace follow-up)
- Advancing the field (unmet needs, next steps)