The mission of the Motility and Cytoskeleton Subgroup is to understand the basic mechanisms that underlie motility and contractility of biological systems. These processes are ultimately the result of molecular motors or contractile filaments that convert chemical energy stored in ATP/GTP into mechanical energy that drives, for example, cell motility, cytokinesis and muscle contraction. The structure and function of the motor families myosin, kinesin and dynein and the cytoskeletal filaments F-actin and microtubules are frequent topics of the annual meetings of the Subgroup. Areas of focus also include the regulatory proteins that control the activity of motors and the cytoskeleton. The Subgroup also annually presents the Motility & Cytoskeleton Early Career Award to reward excellence in the field in early career professionals.