This event brings together people with interest and expertise in quantitative studies of protein-nucleic acid interactions and dynamics in genetic and epigenetic regulation. It intends to bridge statistical and bioinformatic characterization of representative protein-DNA systems with biophysical and biochemical approaches.
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This event will be held on June 10, 2022 from 9:00 am - 12:00 pm US Pacific time.
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This event is organized by BPS member Jin Yu, University of California, Irvine. Elizabeth Read, University of California, Irvine, is co-organizing.
The organizers have set up a website for the event here: https://sites.uci.edu/bsne/
Event Speakers
Anatoly Kolomeisky, Rice U (http://python.rice.edu/~kolomeisky/)
Andy Spakowitz, Stanford (https://web.stanford.edu/~ajspakow/)
Ailong Ke, Cornell (https://sites.google.com/site/kelaboratory/)
Jikui Song, UCR (https://songlab.ucr.edu/)
Zeba Wunderlich, Boston U (https://wunderlichlab.mystrikingly.com/)
Event Schedule
| 9:00 - 9:05 am |
Opening remarks |
| 9:05 - 9:25 am |
Anatoly Kolomeisky from Rice U
HOW PIONEER TRANSCRIPTION FACTORS SEARCH FOR TARGET SITES ON NUCLEOSOMAL DNA |
| 9:25 - 9:45 am |
Andy Spakowitz from Stanford
Impact of Chromosomal Organization on Epigenetic Drift and Domain Stability Revealed by Physics-Based Simulations |
| 9:45 - 10:05 am |
Zeba Wunderlich from Boston U
Molecular Competition in Gene Regulation |
| 10:05 - 10:30 am |
Panel Discussion, optional breakout rooms |
| 10:30 - 10:50 am |
Ailong Ke from Cornell
High-resolution understanding of the spacer acquisition mechanism in CRISPR-Cas systems |
| 10:50 - 11:10 am |
Jikui Song from UCR
The role of substrate deformation in context-dependent non-CG DNA methylation |
| 11:10 - 11:30 am |
Ioan Andricioaei from UCI
Computer Simulations of Protein-DNA Interactions using Kirchhoff's Elastic Rod Theory |
| 11:30 - 12:00 pm |
Panel Discussion |
| 12:00 - 12:30 pm |
Optional breakout rooms |